تناقض چاقی: رخداد بیماری عروق کرونر قلب در مبتلایان به بیماری مزمن کلیوی و سندرم متابولیک
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Abstract:
Background & Objectives: Some studies on chronic diseases have indicated that obesity may result in a paradoxically longer survival. The present study was aimed to investigate the effect of Chronic Kidney Diseases (CKD) and Metabolic Syndrome (MetS) on the incidence of Coronary Heart Disease (CHD). Methods: In order to record time to CHD events, a sample of 6,507 individuals (mean age 47.4 years, 43.4% males) was followed for nearly 10 years. Participants were also categorized into four groups according to presence/absence of CKD and MetS. Then, using a Multivariate Cox Regression, the Hazard Ratio (HR) of each group was estimated relative to individuals free of both CKD and MetS separately for obese (BMI;ge27.1 Kg/m2) and non-obese persons (BMI<27.1 Kg/m2). Results: HR for non-obese patients with CKD but not MetS was obtained 2.06 (95%CI: 1.28-3.31) in men and 2.56 (1.04-6.31) in women. However, these associations were not significant for obese patients. Furthermore, among non-obese men and women with MetS alone, HR was estimated 2.52 (1.71-3.73) and 4.68 (2.20-9.95), respectively. For obese patients, these values were 1.70 (1.05-2.78) and 1.90 (1.16-3.13), respectively. Conclusion: The results reflect that among those who had MetS alone, the risk of CHD incidence was twice higher in non-obese individuals compared to obese patients.
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خطر بیماری مزمن کلیوی و سندرم متابولیک در بروز بیماری عروق کرونر قلب: مطالعه قند و لیپید تهران
Background & Objectives: We studied the risk of Chronic Kidney Disease (CKD), Metabolic Syndrome (MetS), and their interaction on the incidence of Coronary Heart Disease (CHD). Methods: A population of 6568 participants (43.4% male) with a mean age of 48.4 years for males and 46.7 years for females and a median follow-up of 10.1 years was investigated. They were divided into 4 groups at baseli...
full textخطر بیماری مزمن کلیوی و سندرم متابولیک در بروز بیماری عروق کرونر قلب: مطالعه قند و لیپید تهران
مقدمه و اهداف: مطالعات مختلف نشان داده اند که بین بیماری مزمن کلیوی و سندرم متابولیک ارتباط وجود دارد. در این مطالعه به بررسی خطر بیماری مزمن کلیوی و سندرم متابولیک، هم چنین برهم کنش بیماری مزمن کلیوی و سندرم متابولیک در بروز بیماری عروق کرونر قلب پرداخته شد. روش کار: در این مطالعه یک جمعیت 6568 نفری (4/43 درصد مرد) با میانگین سنی 4/48 سال در مردان و 7/46 سال در زنان و با میانه پیگیری 1/10 سال ...
full textخصومت ورزی ، تیپ شخصیتی و بیماری عروق کرونر قلب
Introduction & Objective: In modern medicine, researches in behavioural sciences have described link between psychosocial characteristic, specific personality traits, and development of coronary artery disease. The aim of present study was to investigate the relationship between " hostility" and "type A" personality with acute myocardial infarction. Materials & Methods: In this case-contro...
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Journal title
volume 11 issue None
pages 72- 81
publication date 2015-06
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